Source: Medicines & Healthcare Products Regulatory Agency (GB) Revision Year: 2020 Publisher: Rayner Pharmaceuticals Ltd, 10 Dominion Way, Worthing, West Sussex, BN14 8AQ, United Kingdom
Pharmacotherapeutic Group: Ophthalmologicals, other ophthalmologicals
ATC Code: S01XA08
Acetylcysteine, a derivative of the naturally occurring amino acid L-cysteine, with marked mucolytic properties.
Acetylcysteine has been shown to dramatically reduce the viscosity and tenacity of sputum. The liquifying action is due to the presence of a free sulphydryl group which opens up disulphide bonds present in mucus. This pharmacological action of acetylcysteine is of benefit to patients suffering from ocular mucus abnormality.
This combined with the emollient properties of hypromellose, ensures lubrication and soothing relief for dry eye syndrome.
No specific work has been carried out on the pharmacokinetic properties of acetylcysteine when used as a topical preparation for the eye. Acetylcysteine reduces the viscosity and tenacity of mucus in the eye. This, combined with the emollient properties of hypromellose, ensures lubrication and soothing relief for dry eye syndromes.
There are no preclinical data of relevance to the prescriber which are additional to that already included in other sections of the SPC.
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