Source: Web Search Revision Year: 2011
Kerlone (betaxolol hydrochloride) is a ß1-selective (cardioselective) adrenergic receptor blocking agent available as 10-mg and 20-mg tablets for oral administration. Kerlone is chemically described as 2-propanol, 1-[4-[2-(cyclopropylmethoxy) ethyl] phenoxy]3[(1-methylethyl) amino]-, hydrochloride, (±). It has the following chemical structure:
Betaxolol hydrochloride is a water-soluble white crystalline powder with a molecular formula of C18H29NO3·HCl and a molecular weight of 343.9. It is freely soluble in water, ethanol, chloroform, and methanol, and has a pKa of 9.4.
The inactive ingredients are hydroxypropyl methylcellulose, lactose, magnesium stearate, polyethylene glycol 400, microcrystalline cellulose, colloidal silicon dioxide, sodium starch glycolate, and titanium dioxide.
| How Supplied | ||||||||
|---|---|---|---|---|---|---|---|---|
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Kerlone 10-mg tablets are round, white, film coated, with KERLONE 10 debossed on one side and scored on the other, supplied as:
Kerlone 20-mg tablets are round, white, film coated, with KERLONE 20 debossed on one side and β on the other, supplied as:
Manufactured for: sanofi-aventis U.S. LLC, Bridgewater, NJ 08807 |
| Drug | Countries | |
|---|---|---|
| KERLONE | Germany, France, Tunisia |
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