LOGIMAX Prolonged-release tablet Ref.[28235] Active ingredients: Felodipine Metoprolol

Source: Υπουργείο Υγείας (CY)  Revision Year: 2020  Publisher: Recordati Ireland Ltd, Raheens East, Ringaskiddy, Co. Cork, Ireland Τel.: +353 21 4379 400, Fax: +353 21 4379 264

Product name and form

Logimax 5 mg/50 mg prolonged-release tablets.

Pharmaceutical Form

Prolonged-release tablet.

Logimax prolonged-release tablets contain metoprolol succinate in the form of granules, which each form an individual depot unit, and which together with felodipine are embedded in a polymer. In contact with fluid a gel layer is formed, which permits continuous release of both felodipine and metoprolol.

Appearance

Logimax: apricot-coloured, round, biconvex, marked A/FG, diameter 10 mm.

Qualitative and quantitative composition

1 prolonged-release tablet contains: 5 mg felodipine and metoprolol succinate equivalent to 50 mg metoprolol tartrate.

Excipients with known effect: polyoxyl 40 hydrogenated castor, lactose and sodium.

For the full list of excipients, see section 6.1.

Active Ingredient Description
Felodipine

Felodipine is a vascular selective calcium antagonist, which lowers arterial blood pressure by decreasing systemic vascular resistance. Felodipine is effective in all grades of hypertension.

Metoprolol

Metoprolol is a cardioselective beta-adrenergic blocking agent. It has a relatively greater blocking effect on beta1-receptors (ie those mediating adrenergic stimulation of heart rate and contractility and release of free fatty acids from fat stores) than on beta2-receptors, which are chiefly involved in broncho and vasodilation.

List of Excipients

Colouring agents (titanium dioxide E171, iron oxide E172), lactose anhydrous 42 mg, propyl gallate, silicon dioxide, paraffin, hypromellose, cellulose microcrystalline, ethylcellulose, hydroxypropylcellulose, aluminium sodium silicate, macrogol, sodium stearyl fumarate, polyoxyl 40 hydrogenated castor oil.

Pack sizes and marketing

PVC/PVDC blister packs.

28 tablets.

Marketing authorization holder

Recordati Ireland Ltd, Raheens East, Ringaskiddy, Co. Cork, Ireland Τel.: +353 21 4379 400, Fax: +353 21 4379 264

Marketing authorization dates and numbers

16252

Date of first authorisation: 19 July 1995
Date of latest renewal: 16 September 2011

Drugs

Drug Countries
LOGIMAX Cyprus, Germany, Spain, Finland, France, Hong Kong, Mexico

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