Source: Medicines & Healthcare Products Regulatory Agency (GB) Revision Year: 2019 Publisher: Reig Jofre UK Limited, Unit 9A Caddsdown Business Support Centre, Caddsdown Industrial Park, Bideford, Devon, EX39 3DX, United Kingdom
Fluocinonide is a synthetic anti-inflammatory corticosteroid. Its mechanisms of action are related to vasoconstriction and suppression of membrane permeability, mitotic activity, the immune response and release of inflammatory mediators.
The extent of percutaneous absorption of fluocinonide is determined by many factors including the vehicle, the integrity of the epidermal barrier and the use of occlusive dressings. Following absorption, fluocinonide is metabolised primarily in the liver and excreted by the kidneys.
Fluocinonide is a drug on which extensive clinical experience has been obtained. All relevant information for the prescriber is provided elsewhere in the Summary of Product Characteristics.
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