Source: FDA, National Drug Code (US) Revision Year: 2019
MIGRANAL is ergotamine hydrogenated in the 9,10 position as the mesylate salt. MIGRANAL is known chemically as ergotaman-3', 6', 18-trione, 9,10-dihydro-12'-hydroxy-2'-methyl-5'- (phenylmethyl), (5'α), monomethane-sulfonate. Its molecular weight is 679.78 and its empirical formula is C33H37N5O5•CH4O3.
The chemical structure is:
MIGRANAL (dihydroergotamine mesylate) Nasal Spray is provided for intranasal administration as a clear, colorless to light yellow aqueous solution in an amber glass vial containing:
| dihydroergotamine mesylate | 4 mg |
| caffeine, anhydrous | 10 mg |
| dextrose, anhydrous | 50 mg |
| carbon dioxide | qs |
| purified water | qs 1 mL |
Each milliliter contains: Dihydroergotamine mesylate 4 mg (equivalent to 3.43 mg dihydroergotamine).
| How Supplied |
|---|
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MIGRANAL (dihydroergotamine mesylate) Nasal Spray is available (as a clear, colorless to light yellow aqueous solution) in 3.5 mL amber glass vials containing 4 mg of dihydroergotamine mesylate. MIGRANAL (dihydroergotamine mesylate) Nasal Spray is provided as a package of 8 units, administration instruction sheet, and one package insert. Each unit consists of one vial and one sprayer. (NDC 0187-0245-03) Manufactured for: Bausch Health US, LLC, Bridgewater, NJ 08807 USA Manufactured by: Mipharm, S.p.A., Milano, Italy |
| Drug | Countries | |
|---|---|---|
| MIGRANAL | Austria, Canada, United States, South Africa |
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