NEUROBION Coated tablet Ref.[4437] Active ingredients: Pyridoxine Vitamin B1 Vitamin B12

Posology

One coated tablet once daily. In individual cases, the dose may be increased to one coated tablet 3 times daily.

The coated tablets are to be swallowed whole with plenty of liquid after meals.

Duration of administration

The physician in charge should decide on the duration of administration.

After a maximum period of four weeks, it should be decided whether to reduce the dose. (See section 4.4 ‘Special warnings and precautions for use’).

Paediatric population

Neurobion coated tablets must not be used in children and adolescents (<18 years).

Vitamin B₁

Thiamine has a broad therapeutic range. Very high doses (over 10 g) have a ganglion-blocking effect, similar to that of curare, and suppress the conduction of nerve impulses.

Vitamin B₆

The toxic potential of vitamin B₆ can be considered as very low. Long-term intake (>6-12 months) of a daily dosage >50 mg vitamin B₆ may, however, cause peripheral sensory neuropathy and other sensorial neuropathy syndromes. These symptoms improve gradually upon vitamin discontinuation..

Continuous intake of vitamin B₆ at a daily dosage of more than 1 g over more than two months may produce neurotoxic effects.

Neuropathies with ataxia and sensitivity disorders, cerebral convulsions with EEG changes as well as, in individual cases, hypochromic anaemia and seborrhoeic dermatitis have been described after administration of more than 2 g daily.

Vitamin B₁₂

Allergic reactions, eczematous skin changes and a benign form of acne have been observed after high parenteral doses (in rare cases also after oral doses).

2 years.

Do not store above 25°C.

PVC foil coated with PVDC (40 g/m²)

Aluminum Foil

Water based print primer lacquer outside

Package sizes: 20 coated tablets.

No special requirements.