Source: Medicines & Healthcare Products Regulatory Agency (GB) Revision Year: 2019 Publisher: Focus Pharmaceuticals Ltd, Capital House, 1st Floor, 85 King William Street, London EC4N 7BL, United Kingdom
Secondary prevention of ischaemic stroke and transient ischaemia attacks either alone or in conjunction with aspirin.
An adjunct to oral anti-coagulation for prophylaxis of thromboembolism associated with prosthetic heart valves.
The recommended dose is one capsule twice daily, usually one in the morning and one in the evening.
The capsules should be taken with food. The capsules should be swallowed whole without chewing.
Ofcram PR 200mg Prolonged Release Capsules, Hard is not recommended for children, due to lack of data on safety and efficacy.
No dosage adjustment is needed.
No dosage adjustment is needed.
No dosage adjustment is needed.
For oral administration.
Due to the low number of observations, experience with dipyridamole overdose is limited. Symptoms such as feeling warm, flushes, sweating, restlessness, feeling of weakness, dizziness and angina complaints can be expected. A drop in blood pressure and tachycardia might be observed.
Symptomatic therapy is recommended.
Administration of xanthine derivatives (e.g. aminophylline) may reverse the haemodynamic effects of dipyridamole overdose. ECG monitoring is advised in such a situation.
Due to its wide distribution to tissues and its predominantly hepatic elimination, dipyridamole is not likely to be accessible to enhanced removal procedures.
Unopened: 30 months.
In-use: Discard any capsules remaining 6 weeks after first opening.
Do not store above 25°C.
Keep the container tightly closed in order to protect from moisture.
HDPE bottle with polypropylene child resistant closure, containing a desiccant in a pillow pouch.
Packs contain 60 capsules.
Any unused medicinal product or waste material should be disposed of in accordance with local requirements.
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