Source: Medicines & Healthcare Products Regulatory Agency (GB) Revision Year: 2019 Publisher: Generics [UK] Limited t/a Mylan, Station Close, Potters Bar, Hertfordshire, EN6 1TL, United Kingdom
Pharmacotherapeutic group: Analgesics
ATC code: N02AD01
Pentazocine is an opioid, benzomorphan derivative analgesic with actions and uses similar to those of morphine. It has weak narcotic antagonist actions.
Prolonged use of high doses of pentazocine may produce dependence. It is subject to abuse.
Pentazocine is absorbed from the gastro-intestinal tract.
Following administration by mouth, peak plasma concentrations are reached in 1 to 3 hours. After intramuscular injection, peak plasma concentrations are reached in 15 minutes to 1 hour. Pentazocine diffuses across the placenta.
Pentazocine is metabolised in the liver.
Only a small proportion of the dose administered appears unchanged in the urine.
There are no preclinical safety data of relevance to the prescriber which are additional to that already included in other sections of the SmPC.
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