Source: Health Products Regulatory Authority (ZA) Publisher: PHARMACARE LIMITED, Healthcare Park, Woodlands Drive, Woodmead 2191
Prostatic enlargement, paralytic ileus, pyloric stenosis, closed-angle glaucoma and patients with a narrow angle between the iris and the cornea. Should be used with caution in conditions characterised by tachycardia, such as thyrotoxicosis, cardiac insufficiency or failure, and in cardiac surgery.
In the treatment of Parkinsonism, increases in dosage, and transfer to other forms of treatment should be gradual and anticholinergic medicines should not be withdrawn abruptly. If higher doses provoke severe mental disturbances, the medicine should be discontinued, but minor reactions may be controlled by reducing the dosage until tolerance has developed.
PHENERINE contains lactose monohydrate and sucrose which may have an effect on the glycaemic control of patients with diabetes mellitus.
Patients with the rare hereditary conditions of galactose intolerance e.g. galactosaemia, Lapp lactase deficiency, glucose-galactose malabsorption, sucrase-isomaltase insufficiency or fructose intolerance should not take PHENERINE.
The effects of anticholinergic medicines may be enhanced by the concomitant administration of other medicines with anticholinergic properties, such as amantadine, some antihistaminics, butyrophenones and phenothiazines, and tricyclic anti-depressants.
Not known.
Dryness of the mouth with difficulty in swallowing, thirst, dilatation of the pupils with loss of accommodation and photophobia, increased intra-ocular pressure, flushing and dryness of the skin, bradycardia followed by tachycardia, with palpitations and arrhythmias, a desire to urinate with the inability to do so, as well as reduction in the tone and motility of the gastointestinal tract leading to constipation.
Occasionally vomiting, giddiness and staggering may occur. Retrosternal pain may occur due to increased gastric reflux.
© All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.
