Source: Medicines & Healthcare Products Regulatory Agency (GB) Revision Year: 2011 Publisher: Pharmacosmos A/S, Roervangsvej 30, DK-4300 Holbaek, Denmark
Pharmacotherapeutic group: Drugs for treatment of hyperkalaemia and hyperphosphataemia
ATC code: V03AE
Phosphate binder.
Calcium ions of calcium acetate interact with and bind to phosphates in the gastro-intestinal tract to form calcium phosphate an insoluble or partially soluble product, which is excreted in the faeces.
Both components of Phosex, calcium and acetate, are normal physiological components of the body and are also present in food. As a naturally occurring food constituent, calcium acetate is generally regarded as safe. However, excessive intake of calcium salts can result in hypercalcaemia.
Calcium acetate is not indicated for systemic availability. The residual acetate will be metabolised through bicarbonate, which will be further excreted via normal metabolic routes.
The amount of calcium not involved in the binding of phosphate is variable and any unbound calcium may be absorbed. Therefore regular monitoring of calcium levels is recommended.
No specific studies are available on Phosex calcium acetate tablets.
© All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.
