Source: Medicines & Healthcare Products Regulatory Agency (GB) Revision Year: 1999 Publisher: Macarthys Laboratories Limited, T/A Martindale Pharmaceuticals, Bampton Road, Harold Hill, Romford, RM3 8UG
As a source of potassium ions and phosphate ions in electrolyte replacement therapy.
The normal concentration of serum inorganic phosphate is 3 to 4.5mg (0.03 to 0.045mmol) per 100ml in adults and 4 to 7 mg (0.04 to 0.07mmol) per 100ml in children.
Before administration, the concentrated phosphate injection must be diluted and thoroughly mixed with a larger volume of fluid.
The dose and rate of administration must be individualised.
When used as an electrolyte replenisher, a dose of the equivalent of 10 to 15mmol (310mg to 465mg) of phosphorus a day is usually sufficient to maintain normal serum phosphate, although larger amounts may be required in hypermetabolic states.
The solution should be infused slowly to avoid phosphate intoxication.
As an electrolyte replenisher
The equivalent of 10mmol (310mg) of phosphorus a day by intravenous infusion
As an electrolyte replenisher
The equivalent of 1.5 to 2 mmol (46.5 to 62mg) of phosphorus a day by intravenous infusion.
May result in hyperkalaemia and hyperphosphataemia.
Recommended treatment consists of the following:-
Withholding administration of phosphates
Correcting deficient serum electrolyte concentrations (such as that of calcium)
36 Months.
None noted.
Product is filled into clear colourless 10ml ampoules of Ph.Eur. type I glass.
Packed into cartons of 10 ampoules.
None.
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