SLOW SODIUM Coated tablets Ref.[8049] Active ingredients: Sodium chloride

Source: Medicines & Healthcare Products Regulatory Agency (GB)  Revision Year: 2015  Publisher: HK Pharma Ltd, PO BOX 845, BEDFORD, MK45 9EB

Therapeutic indications

For the treatment and prophylaxis of sodium chloride deficiency.

Posology and method of administration

It is important that the tablets should be swallowed whole with water (approx. 70ml per tablet where kidney function is normal to avoid hypernatraemia), and not chewed.

Adults: For prophylaxis 4-8 tablets per day. For treatment dosage to be adjusted to individual needs up to a maximum of 20 tablets per day in cases of severe salt depletion. For control of muscle cramps during routine maintenance haemodialysis usually 10-16 tablets per dialysis. In some cases of chronic renal salt-wasting up to 20 tablets per day may be required with appropriate fluid intake.

Children: Dosage should be adjusted to individual needs.

Elderly: No special dosage adjustment.

Overdose

Signs and symptoms

Excessive intake of sodium chloride can result in hypernatraemia. Symptoms of hypernatraemia include restlessness, weakness, thirst, reduced salivation and lachrymation, swollen tongue, flushing of the skin, pyrexia, dizziness, headache, oliguria, hypertension, tachycardia, delirium, hyperpnoea and respiratory arrest.

Treatment

Treatment requires the use of sodium-free liquids and the cessation of excessive sodium intake. In the event of a significant overdose serum sodium levels should be evaluated as soon as possible and appropriate steps taken to correct any abnormalities. The use of a loop diuretic e.g. frusemide (with potassium supplementation as required) may be appropriate in severe cases of hypernatraemia. Levels should be monitored until they return to normal.

Shelf life

Five years.

Special precautions for storage

Protect from moisture and store below 30°C. The tablets should be dispensed in moisture proof containers.

Medicines should be kept out of reach of children.

Nature and contents of container

The tablets are available in containers of 100 tablets.

Special precautions for disposal and other handling

None.

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