Source: Health Products Regulatory Authority (IE) Revision Year: 2019 Publisher: Medlock Medical Ltd, Tubiton House, Medlock Street, Oldham, OL1 3HS, United Kingdom
Pharmacotherapeutic group: antiseptics and disinfectants
ATC code: D08AC02
Chlorhexidine is a disinfectant which is effective against a wide range of vegetative Gram-positive and Gram-negative bacteria; it is more effective against Gram-positive than Gram-negative bacteria, some species of Pseudomonas and Proteus being less susceptible. The wide range of organisms against which chlorhexidine is active explains the rationale for presenting it in a solution for swabbing wounds and burns and in obstetrics.
The BP 1993 contains a monograph for chlorhexidine gluconate.
The pharmacokinetics of the compounds when applied to the skin as a topical antiseptic are well described in the literature.
None stated.
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