SUNFLU Tablet Ref.[50590] Active ingredients: Caffeine Chlorphenamine Paracetamol Phenylephrine

Source: Health Sciences Authority (SG)  Revision Year: 2021  Publisher: Sunward Pharmaceutical Pte.Ltd., 11, Wan Lee Road, Singapore, 627943

4.1. Therapeutic indications

It is indicated for the relief of nasal congestion as well as fevers, aches, pains and general discomfort associated with colds and upper respiratory infections.

4.2. Posology and method of administration

Adults: Two tablets every four hours, not to exceed 8 tablets in 24 hours.

4.9. Overdose

Phenylephrine hydrochloride

Overdosage may induce ventricular extrasystoles and short paroxysms of ventricular tachycardia, a sensation of fullness in the head and tingling of the extremities. Should an excessive elevation of blood pressure occur, it may be immediately relieved by an adrenergic blocking agent.

Chlorpheniramine Maleate

Antihistamine overdosage may vary from central nervous system depression (sedation, apnea, cardiovascular collapse) to stimulation (insomnia, hallucinations, tremors or convulsions). Other signs and symptoms may be dizziness, tinnitus, ataxia, blurred vision and hypotension. Stimulation and atropine-like signs and symptoms (dry mouth, fixed, dilated pupils, flushing, hyperthermia and gastrointestinal symptoms) are particularly likely in children.

Treatment

Emergency treatment should be started immediately. Vomiting should be induced, even if it has occured spontaneously. Vomiting by administration of ipecac syrup is preferred. Vomiting should not be induced in patients with impaired conciousness. The action of ipecac is facilitated by physical activity and by the administration of eight to twelve fluid ounces of water. If emesis does not occur within fifteen minutes, the dose of ipecac should be repeated. Precautions against aspiration must be taken, especially in infants and children. Following emesis, any drug remaining in the stomach may be absorbed by activated charcoal administered as a slurry with water. If vomiting is unsuccessful, or contraindicated, gastric lavage should be performed. Isotonic or half isotonic saline are the lavage solution of choice. Saline cathartics, such as milk of magnesia, draw water into the bowel by osmosis and therefore, may be valuable for their action in rapid dilution of bowel content. After emergency treatment the patient should continue to be medically monitored.

Treatment of signs and symptoms of overdosage is symptomatic and supportive.

Stimulants should not be used.

Vasopressors may be used to treat hypotension. Shortacting barbiturates, diazepam or paraldehyde may be administered to control seizures.

Hyperpyrexia, especially in children, may require treatment with tepid water sponges baths or a hypothermia blanket. Apnea is treated with ventilatory support.

6.4. Special precautions for storage

Keep the medicine in airtight container and store in a cool, dry place. Protect from light.

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