Source: FDA, National Drug Code (US) Revision Year: 2021
TENORETIC (atenolol and chlorthalidone) is for the treatment of hypertension. It combines the antihypertensive activity of two agents: a beta1selective (cardioselective) hydrophilic blocking agent (atenolol, TENORMIN) and a monosulfonamyl diuretic (chlorthalidone). Atenolol is Benzeneacetamide, 4[2'-hydroxy-3'-[(1-methylethyl) amino] propoxy]-.
Atenolol (free base) is a relatively polar hydrophilic compound with a water solubility of 26.5 mg/mL at 37°C. It is freely soluble in 1N HCl (300 mg/mL at 25°C) and less soluble in chloroform (3 mg/mL at 25°C).
Chlorthalidone is 2-Chloro-5-(1-hydroxy-3-oxo-1-isoindolinyl) benzene sulfonamide:
Chlorthalidone has a water solubility of 12 mg/100 mL at 20°C.
Each TENORETIC 100 Tablet contains:
Atenolol (TENORMIN) 100 mg
Chlorthalidone 25 mg
Each TENORETIC 50 Tablet contains:
Atenolol (TENORMIN) 50 mg
Chlorthalidone 25 mg
Inactive ingredients: magnesium stearate, microcrystalline cellulose, povidone, sodium starch glycolate.
| How Supplied |
|---|
|
TENORETIC 50 Tablets (atenolol 50 mg and chlorthalidone 25 mg), are white, round, biconvex, uncoated tablets with TENORETIC on one side and 115 on the other side, bisected, supplied in bottles of 90 tablets (NDC 52427-382-90). TENORETIC 100 Tablets (atenolol 100 mg and chlorthalidone 25 mg), are white, round, biconvex, uncoated tablets with TENORETIC on one side and 117 on the other side, supplied in bottles of 90 tablets (NDC 52427-383-90). Distributed by: Almatica Pharma LLC, Morristown, NJ 07960 USA |
| Drug | Countries | |
|---|---|---|
| TENORETIC | Austria, Cyprus, Ecuador, Spain, France, Hong Kong, Italy, Mexico, Nigeria, Tunisia, Turkey, United Kingdom, United States, South Africa |
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