Source: Medicines & Healthcare Products Regulatory Agency (GB) Revision Year: 2017 Publisher: Aspen Pharma Trading Limited, 3016 Lake Drive, Citywest Business Campus, Dublin 24, Ireland
Tioguanine 40 mg Tablets.
| Pharmaceutical Form |
|---|
|
Tioguanine 40 mg Tablets are white to off-white tablet, round, biconvex scored and imprinting ‘T40’ on upper side, without score and debossing on lower side. The scoreline is only to facilitate breaking for ease of swallowing and not to divide into equal doses. |
40 mg tioguanine BP per tablet.
Excipients: This product contains lactose.
For the full list of excipients, see section 6.1.
| Active Ingredient | Description | |
|---|---|---|
| Tioguanine |
Tioguanine is a sulphydryl analogue of guanine and behaves as a purine antimetabolite. It is activated to its nucleotide, thioguanylic acid. Tioguanine metabolites inhibit de novo purine synthesis and purine nucleotide interconversions. Tioguanine is also incorporated into nucleic acids and DNA (deoxyribonucleic acid) incorporation is claimed to contribute to the agent’s cytotoxicity. |
| List of Excipients |
|---|
|
Lactose monohydrate NF |
Amber glass bottles with child-resistant polyethylene/polypropylene closures.
Pack size 25.
Aspen Pharma Trading Limited, 3016 Lake Drive, Citywest Business Campus, Dublin 24, Ireland
PL 39699/ 0045
29 October 1997/1 December 2008
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