Source: European Medicines Agency (EU) Revision Year: 2020 Publisher: KRKA, d.d., Novo mesto, Šmarješka cesta 6, 8501 Novo mesto, Slovenia
Tolucombi 80 mg/25 mg tablets.
| Pharmaceutical Form |
|---|
|
Tablet. White to yellowish white on one side and yellow marbled on the opposite side of two-layer biconvex oval tablet, tablet dimensions 18 mm x 9 mm. |
Each tablet contains 80 mg telmisartan and 25 mg hydrochlorothiazide.
Excipient(s) with known effect:
Each tablet contains 114 mg of lactose (as monohydrate) and 294.08 mg sorbitol (E420).
For the full list of excipients, see section 6.1.
| Active Ingredient | Description | |
|---|---|---|
| Hydrochlorothiazide |
Hydrochlorothiazide is a diuretic with antihypertensive properties. It acts by inhibiting the renal tubular re-absorption of sodium and chloride ions, which are excreted with an accompanying volume of water. Potassium excretion is also promoted. |
|
| Telmisartan |
Telmisartan is an orally active and specific angiotensin II receptor (type AT1) antagonist. Telmisartan selectively binds the AT1 receptor. The binding is long-lasting. |
| List of Excipients |
|---|
|
Hydroxypropylcellulose |
Blisters (OPA/Al/PVC foil//Al foil): 14 × 1, 28 × 1, 30 × 1, 56 × 1, 60 × 1, 84 × 1, 90 × 1, 98 × 1 and 100 × 1 tablet in a box.
Blisters (OPA/Al/PE foil with desiccant//Al foil): 14 × 1 and 98 × 1 tablet in a box. Not all pack sizes may be marketed.
KRKA, d.d., Novo mesto, Šmarješka cesta 6, 8501 Novo mesto, Slovenia
EU/1/13/821/021
EU/1/13/821/022
EU/1/13/821/023
EU/1/13/821/024
EU/1/13/821/025
EU/1/13/821/026
EU/1/13/821/027
EU/1/13/821/028
EU/1/13/821/029
EU/1/13/821/030
EU/1/13/821/033
Date of first authorisation: 13 March 2013
Date of latest renewal: 8 January 2018
| Drug | Countries | |
|---|---|---|
| TOLUCOMBI | Austria, Germany, Estonia, Spain, Finland, Croatia, Ireland, Italy, Lithuania, Poland, Romania, Singapore, United Kingdom |
© All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.
