Source: Health Products Regulatory Authority (IE) Revision Year: 2018 Publisher: Amdipharm Limited, Temple Chambers, 3 Burlington Road, Dublin 4, Ireland.
Valoid is indicated in adults for the prevention and treatment of nausea and vomiting, including:
Valoid may be of value in relieving vomiting and attacks of vertigo associated with Menière’s disease and other forms of vestibular disturbance when the oral route cannot be used.
For the prevention of postoperative nausea and vomiting, administer the first dose by slow intravenous injection 20 minutes before the anticipated end of surgery.
50 mg intramuscularly or intravenously up to three times daily.
When used intravenously, Valoid Injection should be injected slowly into the bloodstream, with only minimal withdrawal of blood into the syringe.
Cyclizine given intravenously, in half the recommended dose, increases the lower oesophageal sphincter tone and thereby reduces the hazard of regurgitation and aspiration of gastric contents if given to patients, undergoing emergency surgery, before induction of general anaesthesia.
There have been no specific studies of Valoid Injection in the elderly. Experience has indicated that normal adult dosage is appropriate.
Not licensed for use in children.
Intramuscularly or intravenously.
Symptoms of acute toxicity from cyclizine arise from peripheral anticholinergic effects and effects on the central nervous system.
Peripheral anticholinergic symptoms include, dry mouth, nose and throat, blurred vision, tachycardia and urinary retention. Central nervous system effects include drowsiness, dizziness, incoordination, ataxia, weakness, hyperexcitability, disorientation, impaired judgement, hallucinations, hyperkinesia, extrapyramidal motor disturbances, convulsions, hyperpyrexia and respiratory depression.
An oral dose of 5 mg/kg is likely to be associated with at least one of the clinical symptoms stated above. Younger children are more susceptible to convulsions. The incidence of convulsions, in children less than five years, is about 60% when the oral dose ingested exceeds 40 mg/kg.
In the management of acute overdosage with Valoid gastric lavage and supportive measures for respiration and circulation should be performed if necessary. Convulsions should be controlled in the usual way with parenteral anticonvulsant therapy
2 years.
Store below 25°C.
Keep the ampoule in the outer carton in order to protect it from direct sunlight.
1 ml neutral glass ampoules.
Five ampoules in a carton.
For single use only. Discard any unused contents.
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