Source: Medicines and Medical Devices Safety Authority (NZ) Revision Year: 2022 Publisher: AFT Pharmaceuticals Ltd, Level 1, 129 Hurstmere Road, Takapuna, Auckland, 0622, New Zealand
Triamcinolone acetonide is a potent fluorinated corticosteroid with rapid anti-inflammatory action, anti-pruritic and anti-allergic actions.
The combined action of the antibiotics neomycin and gramicidin provides comprehensive antibacterial therapy against a wide range of Gram-positive and Gram-negative bacteria, including those microorganisms responsible for most bacterial skin infections.
Nystatin is an antifungal antibiotic, active against a wide range of yeasts and yeast like fungi, including Candida albicans.
The extent of percutaneous absorption of topical corticosteroids is determined by many factors including the vehicle, the integrity of the epidermal barrier, and the use of occlusive dressing.
Topical corticosteroids can be absorbed from normal intact skin. Inflammation and/or other disease processes in the skin increase percutaneous absorption (see Section 4.4, Special Warnings and Precautions for use).
Once absorbed through the skin, topical corticosteroids are handled through the same pharmacokinetic pathways as systemically administered corticosteroids.
Corticosteroids are metabolised primarily in the liver and are then excreted by the kidneys.
Once absorbed, neomycin is rapidly excreted unchanged through the kidneys.
No data available.
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