Source: Medicines & Healthcare Products Regulatory Agency (GB) Revision Year: 2018 Publisher: GlaxoSmithKline Consumer Healthcare (UK) Trading Limited, 980 Great West Road, Brentford, Middlesex, TW8 9GS, United Kingdom
This medicine is an anti-inflammatory and analgesic preparation designed for external application. Due to an aqueous-alcoholic base the gel exerts a soothing and cooling effect.
When this medicine is applied locally, the active substance is absorbed through the skin. In healthy volunteers approximately 6% of the dose applied is absorbed when determined by urinary excretion of diclofenac and its hydroxylated metabolites. Findings in patients confirm that diclofenac penetrates inflamed areas following local application of Voltarol Back and Muscle Pain Relief 1.16% Gel.
Synovial fluid and tissue levels of diclofenac are higher than those detected in plasma.
None known.
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