Source: Medicines & Healthcare Products Regulatory Agency (GB) Revision Year: 2020 Publisher: Cephalon UK Limited, Ridings Point, Whistler Drive, Castleford, West Yorkshire, WF10 5HX, United Kingdom
Zacin 0.025% w/w Cream.
| Pharmaceutical Form |
|---|
|
Cream for topical application. |
Capsaicin 0.025% w/w.
Excipient(s) with known effect:
Each cream tube contains 450 mg benzyl alcohol which is equivalent to 0.01 mg/mg.
Each cream tube contains 3.6g Cetyl alcohol which is equivalent to 0.08 mg/mg
For the full list of excipients, see section 6.1.
| Active Ingredient | Description | |
|---|---|---|
| Capsaicin |
Capsaicin, or 6-nonenamide, N-[(4-hydroxy-3-methoxyphenyl) methyl]-8-methyl, (6E), is a highly selective agonist for the transient receptor potential vanilloid 1 receptor (TRPV1). The initial effect of capsaicin is the activation of TRPV1-expressing cutaneous nociceptors, which results in pungency and erythema due to the release of vasoactive neuropeptides. |
| List of Excipients |
|---|
|
Purified water |
Aluminium tubes with epoxyphenolic lining and polypropylene spiked cap containing 45 g of Zacin Cream 0.025%.
Cephalon UK Limited, Ridings Point, Whistler Drive, Castleford, West Yorkshire, WF10 5HX, United Kingdom
PL 16260/0028
22 March 2010
| Drug | Countries | |
|---|---|---|
| ZACIN | Ireland, United Kingdom |
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