This brand name is authorized in Nigeria.
The drug CHERICOF contains a combination of these active pharmaceutical ingredients (APIs):
1
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UNII
1WS297W6MV - PHENYLEPHRINE
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Phenylephrine is a sympathomimetic agent with mainly direct effects on adrenergic receptors. It has predominantly alpha adrenergic activity and is without stimulating effects on the central nervous system. The sympathomimetic effect of phenylephrine produces vasoconstriction which in turn relieves nasal congestion. |
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UNII
3U6IO1965U - CHLORPHENIRAMINE
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Chlorphenamine is a potent antihistamine (H1-antagonist). Antihistamines diminish or abolish the actions of histamine in the body by competitive reversible blockade of histamine H1-receptor sites on tissues. Chlorphenamine also has anticholinergic activity. |
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3
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UNII
7355X3ROTS - DEXTROMETHORPHAN
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Dextromethorphan is a non-opioid antitussive drug. The major metabolite of dextromethorphan, dextrorphan, binds with high affinity to σ-receptors to produce its antitussive activity without exhibiting the classic opiate effects that occur from binding into μ- and δ-receptors. In larger than therapeutic doses, dextrorphan is also an antagonist of N-methyl-D-aspartate (NMDA) receptors. |
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This drug has been approved in Nigeria as follows:
| Identifier | Form | Presentation | Description | Approval |
|---|---|---|---|---|
| 04-2119 | Syrup | Chericof Cough Formula SYRUP 5 mg/5 mL; 2 mg/5 mL; 10 mg/5 mL | Each 5 mL syrup contains: Chlorpheniramine Maleate 2 mg, Dextromethorphan Hydrobromide 10 mg, Phenylephrine Hydrochloride 5 mg | 01/09/2020 |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| NG | Registered Drug Product Database | 04-2119 |
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