Chemical formula: C₁₉H₁₅NO₆ Molecular mass: 353.326 g/mol PubChem compound: 54676537
Acenocoumarol is a derivative of coumarin used as anticoagulant because acts as an antagonist of vitamin K. Vitamin K antagonists produce their anticoagulant effect by inhibition of the vitamin K-epoxide-reductase with a subsequent reduction of the gammacarboxylation of certain glutamic acid molecules which are located at several sites near the terminal end both of coagulation factors II (prothrombin), VII, IX, and X and of protein C or its cofactor protein S.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| B01AA07 | Acenocoumarol | B Blood and blood forming organs → B01 Antithrombotic agents → B01A Antithrombotic agents → B01AA Vitamin K antagonists |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| SINTHROME Tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Acenocoumarol is an active ingredient of these brands:
Austria (AT)France (FR)Mexico (MX)Poland (PL)Romania (RO)Spain (ES)Tunisia (TN)United Kingdom (UK)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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