Albendazole

Chemical formula: C₁₂H₁₅N₃O₂S  Molecular mass: 265.331 g/mol  PubChem compound: 2082

Therapeutic indications

Albendazole is indicated for:

Echinococcosis

Population group: only adults (18 years old or older)

The long term use of albendazole is indicated for the treatment of hydatid cysts caused by E. granulosus in adults and children over 6 years of age, where surgical intervention is not feasible because of anatomic site or the presence of multiple cysts.

Albendazole shows greatest efficacy in the treatment of liver, lung and peritoneal cysts. Experience with bone cysts or those in the heart or central nervous system is limited, but cases of successful treatment with a prolonged course of albendazole have been reported.

Albendazole may also be used as an adjunct to surgical excision of hydatid cysts either:

  • prior to surgical intervention, or
  • post-operatively, if pre-operative treatment was too short (less than two separate

28-day cycles) or if viable cysts are found at surgery.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Trichuriasis

Population group: only adolescents (12 years - 18 years old) , adults (18 - 65 years old)

Αlbendazole is effective against Trichuriasis.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Ascariasis, filariasis

Population group: only adolescents (12 years - 18 years old) , adults (18 - 65 years old)

Αlbendazole is effective against ascariasis, filariasis.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Echinococcosis

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old)

The long term use of albendazole is indicated for the treatment of hydatid cysts caused by E. granulosus in adults and children over 6 years of age, where surgical intervention is not feasible because of anatomic site or the presence of multiple cysts. Albendazole shows greatest efficacy in the treatment of liver, lung and peritoneal cysts. Experience with bone cysts or those in the heart or central nervous system is limited, but cases of successful treatment with a prolonged course of albendazole have been reported.

Albendazole may also be used as an adjunct to surgical excision of hydatid cysts either:

  • prior to surgical intervention, or
  • post-operatively, if pre-operative treatment was too short (less than two separate 28-day cycles) or if viable cysts are found at surgery.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Neurocysticercosis (NCC)

Population group: only adults (18 - 65 years old)

Αlbendazole is effective in the treatment of neurocysticercosis (NCC) in courses as short as 7 days.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Neurocysticercosis (NCC)

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old)

Αlbendazole is effective in the treatment of neurocysticercosis (NCC) in courses as short as 7 days.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Capillaria philippinensis

Population group: only adults (18 - 65 years old)

Αlbendazole is effective against Capillaria philippinensis in courses of 10 days.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Albendazole is contraindicated in the following cases:

Pregnancy

Pregnancy

Breast feeding

Lactation

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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