Albumin interacts in the following cases:
Albumin should be used with caution in conditions where hypervolaemia and its consequences or haemodilution could represent a special risk for the patient. Examples of such conditions are:
The colloid-osmotic effect of human albumin 200 g/l is approximately four times that of blood plasma. Therefore, when concentrated albumin is administered, care must be taken to assure adequate hydration of the patient. Patients should be monitored carefully to guard against circulatory overload and hyperhydration.
No animal reproduction studies have been conducted with human albumin.
Its safety for use in human pregnancy has not been established in controlled clinical trials and therefore it should only be given with caution to pregnant women. However, clinical experience with albumin suggests that no harmful effects on the course of pregnancy, or on the foetus and the neonate are to be expected.
It is unknown whether human albumin is excreted in human milk. Since human albumin is a normal constituent of human blood, treatment of the nursing mother with human albumin is not expected to present a risk to the breastfed newborn/infant.
No animal reproduction studies have been conducted with human albumin. However, human albumin is a normal constituent of human blood and harmful effects on fertility are not expected.
No effects on the ability to drive and use machines have been observed.
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