Aldesulfone Other names: Sulfoxone Adesulfone

Chemical formula: C₁₄H₁₄N₂Na₂O₆S₃  Molecular mass: 404.482 g/mol  PubChem compound: 5351

Active ingredient description

Sulfoxone is a competitive inhibitor of bacterial enzyme dihydropteroate synthetase. The normal substrate for the enzyme, para-aminobenzoic acid (PABA) cannot bind as usual. The inhibited reaction is necessary in these organisms for the synthesis of folic acid. Aldesulfone sodium (or sulfoxone) is an antibiotic used in the treatment of leprosy.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
J04BA03 Aldesulfone sodium J Antiinfectives for systemic use → J04 Antimycobacterials → J04B Drugs for treatment of lepra → J04BA Drugs for treatment of lepra
Discover more medicines within J04BA03

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 144-76-3
DrugBank Drug: DB01145
KEGG Drug: D02521
PubChem Compound: 5351
SNOMED-CT Concept: 91266006
Aldesulfone (substance)
UNII Identifier: 0G3C18OH4D
SULFOXONE
 
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