Chemical formula: C₁₈H₂₂N₂S Molecular mass: 298.446 g/mol PubChem compound: 5574
There is inadequate evidence of the safety of alimemazine in human pregnancy, but it has been widely used for many years without apparent ill consequence. Some phenothiazines have shown evidence of harmful effects in animals. Alimemazine, like other drugs, should be avoided in pregnancy unless the physician considers it essential. Neuroleptics may occasionally prolong labour and at such a time should be withheld until the cervix is dilated 3-4cm. Possible adverse effects on the neonate include lethargy or paradoxical hyper excitability, tremor and low Apgar score.
Phenothiazines may be excreted in milk: breast feeding should be suspended during treatment.
Patients should be warned about drowsiness during the early days of treatment, and advised not to drive or operate machinery.
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