Aminophylline

Chemical formula: C₁₆H₂₄N₁₀O₄  Molecular mass: 420.426 g/mol  PubChem compound: 9433

Active ingredient description

Aminophylline is a soluble derivative of theophylline and is given for its theophylline activity. Aminophylline relaxes smooth muscle and relieves bronchial spasm. It stimulates the myocardium and reduces venous pressure in congestive heart failure, leading to a marked increase in cardiac output.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
R03DA05 Aminophylline R Respiratory system → R03 Drugs for obstructive airway diseases → R03D Other systemic drugs for obstructive airway diseases → R03DA Xanthines
Discover more medicines within R03DA05

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
AMINOPHYLLINE INJECTION BP Injection Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 317-34-0
CAS Substance: 49746-06-7
DrugBank Drug: DB01223
KEGG Drug: D00227
PubChem Compound: 9433
RxNorm Ingredient: 689
SNOMED-CT Concept: 373508009
Aminophylline (substance)
UNII Identifier: 27Y3KJK423
AMINOPHYLLINE

Medicines

Aminophylline is an active ingredient of these brands:

Brazil (BR)

Estonia (EE)

Finland (FI)

Hong Kong (HK)

Ireland (IE)

Japan (JP)

Lithuania (LT)

Mexico (MX)

Romania (RO)

South Africa (ZA)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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