Amphotericin B

Chemical formula: C₄₇H₇₃NO₁₇  Molecular mass: 924.079 g/mol  PubChem compound: 5280965

Therapeutic indications

Amphotericin B is indicated for:

Severe systemic and/or deep mycoses

Population group: only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

Amphotericin B is indicated in adults and children aged 1 month to 18 years old for the treatment of severe systemic and/or deep mycoses.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Mucormycosis

Population group: only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

Mucormycosis

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Visceral leishmaniasis

Population group: only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

Amphotericin B is indicated for the treatment of visceral leishmaniasis in immunocompetent patients including both adults and children.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Mycosis in febrile neutropenia

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

Amphotericin B is indicated in adults and children aged 1 month to 18 years old for the empirical treatment of presumed fungal infections in febrile neutropenic patients, where the fever has failed to respond to broad spectrum antibiotics and appropriate investigations have failed to define a bacterial or viral cause.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Amphotericin B is contraindicated in the following cases:

Hypersensitivity to amphotericin B

Amphotericin allergy

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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