Antithymocyte immunoglobulin Other names: ATG Anti-thymocyte globulin

Active ingredient description

Antithymocyte immunoglobulin is a selective immunosuppressive agent mostly acting on T lymphocytes. Antithymocyte immunoglobulin is used for the prevention and treatment of graft rejection after solid organ transplantation, usually in combination with other immunosuppressive drugs.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
L04AA04 Antithymocyte immunoglobulin (rabbit) L Antineoplastic and immunomodulating agents → L04 Immunosuppressants → L04A Immunosuppressants → L04AA Selective immunosuppressants
Discover more medicines within L04AA04

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
ATGAM Concentrate for solution for infusion FDA, National Drug Code (US) MPI, US: SPL/PLR
THYMOGLOBULINE Powder for solution for infusion Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

External identifiers

CAS Substance: 308067-60-9
DrugBank Drug: DB00098
RxNorm Ingredient: 107044
SNOMED-CT Concept: 768651008
Antithymocyte immunoglobulin (substance)
UNII Identifier: D7RD81HE4W
LAPINE T-LYMPHOCYTE IMMUNE GLOBULIN

Medicines

Antithymocyte immunoglobulin is an active ingredient of these brands:

United States (US)

  • ATGAM as EQUINE THYMOCYTE IMMUNE GLOBULIN

Austria (AT)

Brazil (BR)

Canada (CA)

  • ATGAM as EQUINE THYMOCYTE IMMUNE GLOBULIN

Croatia (HR)

Cyprus (CY)

Ecuador (EC)

Estonia (EE)

France (FR)

Hong Kong (HK)

  • ATGAM as EQUINE THYMOCYTE IMMUNE GLOBULIN

Ireland (IE)

Israel (IL)

Japan (JP)

  • ATGAM as EQUINE THYMOCYTE IMMUNE GLOBULIN
  • THYMOGLOBULINE as Human anti-thymocyte rabbit immunoglobulin

Lithuania (LT)

Malta (MT)

Netherlands (NL)

New Zealand (NZ)

  • ATGAM as EQUINE THYMOCYTE IMMUNE GLOBULIN

Poland (PL)

Romania (RO)

Singapore (SG)

  • ATGAM as EQUINE THYMOCYTE IMMUNE GLOBULIN
  • THYMOGLOBULINE as Human anti-thymocyte rabbit immunoglobulin

South Africa (ZA)

  • ATGAM as EQUINE THYMOCYTE IMMUNE GLOBULIN
  • THYMOGLOBULINE as Human anti-thymocyte rabbit immunoglobulin

Spain (ES)

Tunisia (TN)

Turkey (TR)

United Kingdom (UK)

  • ATGAM as EQUINE THYMOCYTE IMMUNE GLOBULIN

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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