Chemical formula: C₇H₁₁N₃O₆S Molecular mass: 265.24 g/mol PubChem compound: 9835049
Animal studies with avibactam have shown reproductive toxicity without evidence of teratogenic effects.
Avibactam should only be used during pregnancy if the potential benefit outweighs the possible risk.
It is unknown whether avibactam is excreted in human milk. A risk to newborns/infants cannot be excluded. A decision must be made whether to discontinue breast feeding or to discontinue/abstain from avibactam therapy taking into account the benefit of breast feeding for the child and the benefit of therapy for the woman.
The effects of avibactam on fertility in humans have not been studied. Animal studies with avibactam do not indicate harmful effects with respect to fertility.
Undesirable effects may occur (e.g. dizziness), which may influence the ability to drive and use machines following administration of avibactam.
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