Baricitinib

Chemical formula: C₁₆H₁₇N₇O₂S  Molecular mass: 371.42 g/mol  PubChem compound: 44205240

Therapeutic indications

Baricitinib is indicated for:

Rheumatoid arthritis

Population group: only adults (18 years old or older)

Baricitinib is indicated for the treatment of moderate to severe active rheumatoid arthritis in adult patients who have responded inadequately to, or who are intolerant to one or more disease-modifying anti-rheumatic drugs. Baricitinib may be used as monotherapy or in combination with methotrexate.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Moderate to severe atopic dermatitis

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

Baricitinib is indicated for the treatment of moderate to severe atopic dermatitis in adult and paediatric patients 2 years of age and older who are candidates for systemic therapy.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Alopecia areata

Population group: only adults (18 years old or older)

Baricitinib is indicated for the treatment of severe alopecia areata in adult patients.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Juvenile idiopathic arthritis

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old)

Baricitinib is indicated for the treatment of active juvenile idiopathic arthritis in patients 2 years of age and older who have had an inadequate response or intolerance to one or more prior conventional synthetic or biologic DMARDs:

  • Polyarticular juvenile idiopathic arthritis (polyarticular rheumatoid factor positive [RF+] or negative [RF-], extended oligoarticular),
  • Enthesitis-related arthritis, and
  • Juvenile psoriatic arthritis.

Baricitinib may be used as monotherapy or in combination with methotrexate.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Baricitinib is contraindicated in the following cases:

Pregnancy

Pregnancy

Lactation

Lactation

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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