Belimumab

Chemical formula: C₆₇₁₄H₁₀₄₂₈O₂₁₀₂S₅₂ 

Therapeutic indications

Belimumab is indicated for:

Systemic lupus erythematosus

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

Belimumab is indicated as add-on therapy in patients aged 5 years and older with active, autoantibody-positive systemic lupus erythematosus (SLE) with a high degree of disease activity (e.g., positive anti-dsDNA and low complement) despite standard therapy.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Active lupus nephritis

Population group: only adults (18 years old or older)

Belimumab is indicated in combination with background immunosuppressive therapies for the treatment of adult patients with active lupus nephritis.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Belimumab is contraindicated in the following cases:

Live vaccines

Live organism vaccines

Active serious infections

Infectious disease

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