Benzathine benzylpenicillin Other names: Penicillin G benzathine

Molecular mass: 334.39 g/mol 

Active ingredient description

Semisynthetic antibiotic prepared by combining the sodium salt of penicillin G with N,N'-dibenzylethylenediamine. Benzathine benzylpenicillin binds to penicillin binding proteins (PBP), the enzymes that catalyze the synthesis of peptidoglycan, a critical component of the bacterial cell wall. This leads to the interruption of cell wall synthesis, consequently leading to bacterial cell growth inhibition and cell lysis.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
J01CE08 Benzathine benzylpenicillin J Antiinfectives for systemic use → J01 Antibacterials for systemic use → J01C Beta-lactam antibacterials, penicillins → J01CE Beta-lactamase sensitive penicillins
Discover more medicines within J01CE08

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
BICILLIN L-A Suspension for injection FDA, National Drug Code (US) MPI, US: SPL/Old

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 1538-09-6
KEGG Drug: D02157
RxNorm Ingredient: 7982
SNOMED-CT Concept: 75247008
Benzathine benzylpenicillin (substance)
UNII Identifier: RIT82F58GK
PENICILLIN G BENZATHINE

Medicines

Benzathine benzylpenicillin is an active ingredient of these brands:

United States (US)

Australia (AU)

Austria (AT)

Brazil (BR)

Canada (CA)

Cyprus (CY)

Ecuador (EC)

Estonia (EE)

France (FR)

Japan (JP)

Malta (MT)

New Zealand (NZ)

Poland (PL)

Romania (RO)

South Africa (ZA)

Spain (ES)

Tunisia (TN)

Turkey (TR)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

 
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