Benzatropine

Chemical formula: C₂₁H₂₅NO  Molecular mass: 307.429 g/mol  PubChem compound: 1201549

Pharmacodynamic properties

Benzatropine possesses both anticholinergic and antihistaminic effects, although only the former have been established as therapeutically significant in the management of parkinsonism.

Preclinical safety data

In the isolated guinea pig ileum, the anticholinergic activity of this drug is about equal to that of atropine; however, when administered orally to unanesthetized cats, it is only about half as active as atropine.

In laboratory animals, its antihistaminic activity and duration of action approach those of pyrilamine maleate.

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