Chemical formula: C₉H₁₁NO₂ Molecular mass: 165.189 g/mol PubChem compound: 2337
Benzocaine is a local anaesthetic of the ester type, acting to produce reversible loss of sensation by preventing or diminishing the generation and transmission of sensory nerve impulses near the site of application. Depolarisation of the neuronal membrane and ion exchange are reversibly inhibited.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| C05AD03 | Benzocaine | C Cardiovascular system → C05 Vasoprotectives → C05A Agents for treatment of hemorrhoids and anal fissures for topical use → C05AD Local anesthetics |
| D04AB04 | Benzocaine | D Dermatologicals → D04 Antipruritics, incl. antihistamines, anesthetics, etc. → D04A Antipruritics, incl. antihistamines, anesthetics, etc. → D04AB Anesthetics for topical use |
| N01BA05 | Benzocaine | N Nervous system → N01 Anesthetics → N01B Anesthetics, local → N01BA Esters of aminobenzoic acid |
| R02AD01 | Benzocaine | R Respiratory system → R02 Throat preparations → R02A Throat preparations → R02AD Anesthetics, local |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| LANACANE Creme | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| ULTRA CHLORASEPTIC ANAESTHETIC THROAT SPRAY 0.71% Oromucosal Spray | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| ORAJEL Dental gel | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Benzocaine is an active ingredient of these brands:
Austria (AT)
Brazil (BR)Cyprus (CY)
Ecuador (EC)
Estonia (EE)
Hong Kong (HK)
Israel (IL)
Japan (JP)
Lithuania (LT)
Malta (MT)Mexico (MX)Poland (PL)
Romania (RO)
Singapore (SG)
Spain (ES)
Turkey (TR)
United Kingdom (UK)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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