Bivalirudin

Chemical formula: C₉₈H₁₃₈N₂₄O₃₃  Molecular mass: 2,180.285 g/mol  PubChem compound: 16129704

Therapeutic indications

Bivalirudin is indicated for:

Treatment of adult patients with unstable angina/non-ST segment elevation myocardial infarction

Population group: only adults (18 years old or older)

Bivalirudin is indicated for the treatment of adult patients with unstable angina/non-ST segment elevation myocardial infarction (UA/NSTEMI) planned for urgent or early intervention.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Percutaneous coronary intervention

Population group: only adults (18 years old or older)

Bivalirudin is indicated as an anticoagulant in adult patients undergoing percutaneous coronary intervention (PCI), including patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary PCI.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Bivalirudin is contraindicated in the following cases:

Severe renal impairment (GFR<30 ml/min), renal dialysis

at least one of

Renal failure stage 5: Kidney failure (GFR <15 mL/min/1.73 m2 or dialysis)
Renal dialysis

Severe uncontrolled hypertension

Hypertension

Subacute bacterial endocarditis

Subacute bacterial endocarditis

Active bleeding, increased risk of bleeding, haemostasis disorders, coagulation disorders

at least one of
Bleeding
High risk of hemorrhage
Blood coagulation disorder

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