Boceprevir

Chemical formula: C₂₇H₄₅N₅O₅  Molecular mass: 519.677 g/mol  PubChem compound: 10324367

Active ingredient description

Boceprevir is an inhibitor of the HCV NS3 protease. Boceprevir covalently, yet reversibly, binds to the NS3 protease active site serine (Ser139) through a (alpha)-ketoamide functional group to inhibit viral replication in HCV-infected host cells.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
J05AP03 J Antiinfectives for systemic use → J05 Antivirals for systemic use → J05A Direct acting antivirals → J05AP Antivirals for treatment of HCV infections
Discover more medicines within J05AP03

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 394730-60-0
DrugBank Drug: DB08873
KEGG Drug: D08876
PubChem Compound: 10324367
RxNorm Ingredient: 1102129
SNOMED-CT Concept: 698183007
Boceprevir (substance)
UNII Identifier: 89BT58KELH
BOCEPREVIR

Medicines

Boceprevir is an active ingredient of these brands:

Estonia (EE)

Lithuania (LT)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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