Brentuximab vedotin

Therapeutic indications

Brentuximab vedotin is indicated for:

Previously untreated Hodgkin lymphoma (HL) CD30+

Population group: only adults (18 years old or older)

Brentuximab vedotin is indicated for adult patients with previously untreated CD30+ Stage III or IV Hodgkin lymphoma (HL) in combination with doxorubicin, vinblastine and dacarbazine (AVD).

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Previously untreated systemic anaplastic large cell lymphoma (sALCL)

Population group: only adults (18 years old or older)

Brentuximab vedotin in combination with cyclophosphamide, doxorubicin and prednisone (CHP) is indicated for adult patients with previously untreated systemic anaplastic large cell lymphoma (sALCL).

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Cutaneous T-cell lymphoma (CTCL) with CD30+

Population group: only adults (18 years old or older)

Brentuximab is indicated for the treatment of adult patients with CD30+ cutaneous T-cell lymphoma (CTCL) after at least 1 prior systemic therapy.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Hodgkin lymphoma (HL) CD30+ at increased risk of relapse or progression

Population group: only adults (18 years old or older)

Brentuximab vedotin is indicated for the treatment of adult patients with CD30+ HL at increased risk of relapse or progression following autologous stem cell transplant (ASCT).

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Relapsed or refractory Hodgkin lymphoma (HL) CD30+

Population group: only adults (18 years old or older)

Brentuximab vedotin is indicated for the treatment of adult patients with relapsed or refractory CD30+ Hodgkin lymphoma (HL):

1. following ASCT, or

2. following at least two prior therapies when ASCT or multi-agent chemotherapy is not a treatment option.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Relapsed or refractory systemic anaplastic large cell lymphoma (sALCL)

Population group: only adults (18 years old or older)

Brentuximab vedotin is indicated for the treatment of adult patients with relapsed or refractory sALCL.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Brentuximab vedotin is contraindicated in the following cases:

Lactation

Lactation

Bleomycin

Bleomycin

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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