Brexucabtagene autoleucel

Therapeutic indications

Brexucabtagene autoleucel is indicated for:

Mantle cell lymphoma

Population group: only adults (18 years old or older)

Tecartus is indicated for the treatment of adult patients with relapsed or refractory mantle cell lymphoma (MCL) after two or more lines of systemic therapy including a Bruton’s tyrosine kinase (BTK) inhibitor.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Precursor B-cell acute lymphoblastic leukemia

Population group: only adults (18 years old or older)

Brexucabtagene autoleucel is indicated for the treatment of adult patients 26 years of age and above with relapsed or refractory B-cell precursor acute lymphoblastic leukaemia (ALL).

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Brexucabtagene autoleucel is contraindicated in the following cases:

Pregnancy

Pregnancy

Effects on ability to drive and use machines

Effects on ability to drive and use machines

Unresolved serious adverse reactions, infection, inflammatory disease, active graft-versus-host disease

at least one of
Lung disorder
Heart disease
Infectious disease
Inflammatory disorder
Graft versus host disease

Blood, organ, tissue and cell donation

at least one of
Blood unit collection
Organ retrieval operation
Transplantation

Live virus vaccines

Live viral vaccines

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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Summary of Product Characteristics (SPC) 2024: TECARTUS Dispersion for infusion
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