Buspirone Other names: Buspirone hydrochloride

Chemical formula: C₂₁H₃₁N₅O₂  Molecular mass: 385.503 g/mol  PubChem compound: 2477

Active ingredient description

Buspirone is an azaspirodecanedione. The exact mechanism of buspirone anxioselective action is not fully known. From animal studies it is known to interact with serotonin, noradrenaline (norepinephrine), acetylcholine and dopamine systems of the brain.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
N05BE01 Buspirone N Nervous system → N05 Psycholeptics → N05B Anxiolytics → N05BE Azaspirodecanedione derivatives
Discover more medicines within N05BE01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
BUSPIRONE Tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 33386-08-2
CAS Substance: 36505-84-7
DrugBank Drug: DB00490
KEGG Drug: D07593
PubChem Compound: 2477
RxNorm Ingredient: 1827
SNOMED-CT Concept: 387523009
Buspirone (substance)
UNII Identifier: TK65WKS8HL
BUSPIRONE

Medicines

Buspirone is an active ingredient of these brands:

Brazil (BR)

  • ANSITEC as BUSPIRONE HYDROCHLORIDE

Estonia (EE)

Finland (FI)

Germany (DE)

  • ANXUT as BUSPIRONE HYDROCHLORIDE

Israel (IL)

  • SORBON as BUSPIRONE HYDROCHLORIDE

Lithuania (LT)

Malta (MT)

  • LOXAPIN as BUSPIRONE HYDROCHLORIDE

Poland (PL)

Romania (RO)

South Africa (ZA)

  • ASTRID as BUSPIRONE HYDROCHLORIDE
  • PASRIN as BUSPIRONE HYDROCHLORIDE

Turkey (TR)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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