Calcidiol Other names: Calcifediol Calcifidiol

Chemical formula: C₂₇H₄₄O₂  Molecular mass: 400.637 g/mol  PubChem compound: 5283731

Active ingredient description

Vitamin D3 must undergo a two-step metabolic process to be active; the first step occurs in the microsomal fraction of the liver where Vitamin D is hydroxylated at position 25 (25-hydroxycholecalciferol or calcifediol); the second step takes place in the kidney where 1,25-dihydroxycholecalciferol or calcitriol is formed due to the activity of enzyme 25-hydroxycholecalciferol 1-hydroxylase. Vitamin D increases absorption of calcium and phosphorus in the intestine and improves normal bone formation and mineralization.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
A11CC06 Calcifediol A Alimentary tract and metabolism → A11 Vitamins → A11C Vitamin A and D, incl. combinations of the two → A11CC Vitamin D and analogues
Discover more medicines within A11CC06
H05BX05 H Systemic hormonal preparations, excl. Sex hormones and insulins → H05 Calcium homeostasis → H05B Anti-parathyroid agents → H05BX Other anti-parathyroid agents
Discover more medicines within H05BX05

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 19356-17-3
DrugBank Drug: DB00146
PubChem Compound: 5283731
RxNorm Ingredient: 1889
SNOMED-CT Concept: 259337002
Calcifediol (substance)
UNII Identifier: P6YZ13C99Q
CALCIFEDIOL

Medicines

Calcidiol is an active ingredient of these brands:

United States (US)

Croatia (HR)

Ecuador (EC)

Estonia (EE)

France (FR)

Ireland (IE)

Poland (PL)

Romania (RO)

Spain (ES)

Tunisia (TN)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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