Molecular mass: 1,321.412 g/mol PubChem compound: 3000502
Capreomycin is active against human strains of Mycobacterium tuberculosis.
Capreomycin sulphate is not significantly absorbed from the gastrointestinal tract, and must be administered parenterally.
Following intramuscular injection of 1g of capreomycin in human subjects, peak serum concentrations in the range of 20-50µg/ml are achieved after 1-2 hours. Serum concentrations are low at 24 hours and daily injections of 1g for 30 days produced no significant accumulation in subjects with normal renal function.
Capreomycin is excreted in the urine, essentially unaltered, and approximately 50% of a 1g intramuscular dose is excreted within 12 hours.
There are no preclinical data.
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