Cefotaxime Other names: Cephotaxime

Chemical formula: C₁₆H₁₇N₅O₇S₂  Molecular mass: 455.465 g/mol  PubChem compound: 5742673

Active ingredient description

Cefotaxime exerts its action by binding to one or more of the penicillin-binding proteins (PBPs) which in turn inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls, thereby inhibiting cell wall synthesis.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
J01DD01 Cefotaxime J Antiinfectives for systemic use → J01 Antibacterials for systemic use → J01D Other beta-lactam antibacterials → J01DD Third-generation cephalosporins
Discover more medicines within J01DD01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
CEFOTAXIME 1g Powder for solution for injection or infusion Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 63527-52-6
CAS Substance: 64485-93-4
DrugBank Drug: DB00493
KEGG Drug: D07647
PubChem Compound: 5742673
RxNorm Ingredient: 2186
SNOMED-CT Concept: 372704003
Cefotaxime (substance)
UNII Identifier: N2GI8B1GK7
CEFOTAXIME

Medicines

Cefotaxime is an active ingredient of these brands:

Austria (AT)

Brazil (BR)

Cyprus (CY)

Estonia (EE)

Hong Kong (HK)

Ireland (IE)

Italy (IT)

Japan (JP)

Lithuania (LT)

Malta (MT)

Mexico (MX)

Poland (PL)

Singapore (SG)

South Africa (ZA)

Spain (ES)

Tunisia (TN)

Turkey (TR)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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