Chloral hydrate

Chemical formula: C₂H₃Cl₃O₂  Molecular mass: 165.403 g/mol  PubChem compound: 2707

Pregnancy

Chloral hydrate should not be used in pregnancy.

Nursing mothers

Chloral hydrate should not be used in lactation.

Effects on ability to drive and use machines

Patients receiving chloral hydrate should be warned that their ability to drive or use machinery may be impaired by drowsiness.

Adverse reactions


Gastric irritation, abdominal distension and flatulence may occur. Excitement, tolerance, allergic skin reactions, headache and ketonuria have occasionally been reported. There is a danger of abuse or chronic intoxication and the possibility that habituation may develop. In such patients gastritis and parenchymatous renal injury may develop. After long term use, sudden withdrawal may result in delirium.

Elderly patients are more susceptible to the undesirable effects of hypnotic medications such as chloral hydrate and are therefore more susceptible to ataxia, confusion, falls and injuries.

Cross-check medications

Review your medication to ensure that there are no potentially harmful drug interactions or contraindications.

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