Ciclopirox olamine

Chemical formula: C₁₂H₁₇NO₂  Molecular mass: 207.269 g/mol  PubChem compound: 2749

Active ingredient description

Ciclopirox is a hydroxypyridone antifungal agent which is active in vitro inhibiting the growth of various fungal species including the yeast Malassezia furfur (formerly known as Pityrosporum ovale or Pityrosporum orbiculare).

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
D01AE14 Ciclopirox D Dermatologicals → D01 Antifungals for dermatological use → D01A Antifungals for topical use → D01AE Other antifungals for topical use
Discover more medicines within D01AE14
G01AX12 Ciclopirox G Genito urinary system and sex hormones → G01 Gynecological antiinfectives and antiseptics → G01A ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS
Discover more medicines within G01AX12

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
LOPROX Shampoo FDA, National Drug Code (US) MPI, US: SPL/PLR
LOPROX Cream FDA, National Drug Code (US) MPI, US: SPL/Old
LOPROX Topical suspension FDA, National Drug Code (US) MPI, US: SPL/Old
STIEPROX Shampoo Health Products Regulatory Authority (IE) MPI, EU: SmPC
PENLAC Nail lacquer FDA, National Drug Code (US) MPI, US: SPL/Old

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 29342-05-0
CAS Substance: 41621-49-2
DrugBank Drug: DB01188
KEGG Drug: D03488
PubChem Compound: 2749
RxNorm Ingredient: 21090
SNOMED-CT Concept: 372854000
Ciclopirox (substance)
UNII Identifier: 19W019ZDRJ
CICLOPIROX

Medicines

Ciclopirox olamine is an active ingredient of these brands:

United States (US)

Brazil (BR)

Canada (CA)

Croatia (HR)

  • OXOLAM as CICLOPIROX OLAMINE

Cyprus (CY)

Ecuador (EC)

Estonia (EE)

Finland (FI)

France (FR)

Germany (DE)

Ireland (IE)

Israel (IL)

Malta (MT)

Mexico (MX)

  • LOPROX as CICLOPIROX OLAMINE

Netherlands (NL)

  • LOPROX as CICLOPIROX OLAMINE

New Zealand (NZ)

Poland (PL)

Romania (RO)

Spain (ES)

Tunisia (TN)

Turkey (TR)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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