Chemical formula: C₆₅H₈₂N₂O₁₈S₂ Molecular mass: 929.16 g/mol PubChem compound: 62886
Cisatracurium is an intermediate-duration, non-depolarising benzylisoquinolinium skeletal muscle relaxant. Cisatracurium binds to cholinergic receptors on the motor end-plate to antagonise the action of acetylcholine, resulting in a competitive block of neuromuscular transmission. This action is readily reversed by anti-cholinesterase agents such as neostigmine or edrophonium.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| M03AC11 | Cisatracurium | M Musculo-skeletal system → M03 Muscle relaxants → M03A Muscle relaxants, peripherally acting agents → M03AC Other quaternary ammonium compounds |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| CISATRACURIUM Solution for injection/infusion | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| NIMBEX Solution for injection / infusion | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Cisatracurium is an active ingredient of these brands:
United States (US)Austria (AT)Cyprus (CY)Finland (FI)France (FR)Ireland (IE)Lithuania (LT)Mexico (MX)Netherlands (NL)Poland (PL)Singapore (SG)Spain (ES)United Kingdom (UK)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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