Clemastine

Chemical formula: C₂₁H₂₆ClNO  Molecular mass: 343.89 g/mol  PubChem compound: 26987

Active ingredient description

Clemastine is an H1-receptor antagonist. It inhibits selectively the histamine receptors of the H1 type and reduces capillary permeability. It exerts a potent antihistaminic and antipruritic effect with a fast onset and long duration of action.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
D04AA14 Clemastine D Dermatologicals → D04 Antipruritics, incl. antihistamines, anesthetics, etc. → D04A Antipruritics, incl. antihistamines, anesthetics, etc. → D04AA Antihistamines for topical use
Discover more medicines within D04AA14
R06AA04 Clemastine R Respiratory system → R06 Antihistamines for systemic use → R06A Antihistamines for systemic use → R06AA Aminoalkyl ethers
Discover more medicines within R06AA04

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
TAVEGIL Tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 15686-51-8
DrugBank Drug: DB00283
KEGG Drug: D03535
PubChem Compound: 26987
RxNorm Ingredient: 2578
SNOMED-CT Concept: 372744005
Clemastine (substance)
UNII Identifier: 95QN29S1ID
CLEMASTINE

Medicines

Clemastine is an active ingredient of these brands:

Brazil (BR)

  • (combination) EMISTIN as CLEMASTINE FUMARATE

Ecuador (EC)

Estonia (EE)

Germany (DE)

Hong Kong (HK)

  • ZEMIN as CLEMASTINE FUMARATE

Japan (JP)

Lithuania (LT)

Netherlands (NL)

South Africa (ZA)

Turkey (TR)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

© All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.