Chemical formula: C₂₁H₂₃Cl₂NO₆ Molecular mass: 456.316 g/mol PubChem compound: 153994
Clevidipine is a dihydropyridine L-type calcium channel blocker. L-type calcium channels mediate the influx of calcium during depolarization in arterialsmooth muscle. Experiments in anesthetized rats and dogs show that clevidipine reduces mean arterial blood pressure by decreasing systemic vascular resistance.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| C08CA16 | C Cardiovascular system → C08 Calcium channel blockers → C08C Selective calcium channel blockers with mainly vascular effects → C08CA Dihydropyridine derivatives | |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| CLEVIPREX Emulsion for infusion | FDA, National Drug Code (US) | MPI, US: SPL/PLR |
Clevidipine is an active ingredient of these brands:
United States (US)Austria (AT)France (FR)Netherlands (NL)New Zealand (NZ)Spain (ES)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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