Clofedanol Other names: Chlophedianol

Chemical formula: C₁₇H₂₀ClNO  Molecular mass: 289.8 g/mol  PubChem compound: 2795

Active ingredient description

Clofedanol is a centrally-acting cough suppressant, although the mechanism of action is not known. Clofedanol suppresses the cough reflex by a direct effect on the cough center in the medulla of the brain. It also has local anesthetic and antihistamine properties, and may have anticholinergic effects at high doses.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
R05DB10 Clofedanol R Respiratory system → R05 Cough and cold preparations → R05D Cough suppressants, excl. combinations with expectorants → R05DB Other cough suppressants
Discover more medicines within R05DB10

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 791-35-5
DrugBank Drug: DB04837
PubChem Compound: 2795
RxNorm Ingredient: 21254
SNOMED-CT Concept: 61398007
Clofedanol (substance)
UNII Identifier: 42C50P12AP
CHLOPHEDIANOL

Medicines

Clofedanol is an active ingredient of these brands:

Canada (CA)

  • ULONE as CHLOPHEDIANOL HYDROCHLORIDE

Hong Kong (HK)

  • COLDRIN as CHLOPHEDIANOL HYDROCHLORIDE

Japan (JP)

  • COLDRIN as CHLOPHEDIANOL HYDROCHLORIDE

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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